o-nitrophenyl Cellobioside as an Active Site Probe for Family 7 Cellobiohydrolaseso-nitrophenyl Cellobioside as an Active Site Probe for Family 7 Cellobiohydrolases

Structural highlights

4v0z is a 1 chain structure with sequence from Trichoderma reesei qm9414. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , ,
NonStd Res:
Activity:Cellulose 1,4-beta-cellobiosidase (reducing end), with EC number 3.2.1.176
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[GUX1_HYPJE] The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.

4v0z, resolution 1.70Å

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OCA