2eg9

Crystal structure of the truncated extracellular domain of mouse CD38Crystal structure of the truncated extracellular domain of mouse CD38

Structural highlights

2eg9 is a 2 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:	Cd38 (LK3 transgenic mice)
Activity:	NAD(+) nucleosidase, with EC number 3.2.2.5
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, TOPSAN

Function

[CD38_MOUSE] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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OCA