1q7j

Structural Analysis of Integrin alpha IIb beta 3- Disintegrin with the AKGDWN MotifStructural Analysis of Integrin alpha IIb beta 3- Disintegrin with the AKGDWN Motif

Structural highlights 1q7j is a 1 chain structure with sequence from Agkistrodon rhodostoma. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 1q7i Gene: RHOD (Agkistrodon rhodostoma) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Function [VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Disintegrin

spinqualitylabelsall models 1q7j, 20 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image