1xm3

From Proteopedia
Revision as of 05:25, 10 September 2015 by OCA (talk | contribs)
Jump to navigation Jump to search

Crystal structure of Northeast Structural Genomics Target SR156Crystal structure of Northeast Structural Genomics Target SR156

Structural highlights

1xm3 is a 4 chain structure with sequence from "bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
NonStd Res:
Gene:thiG ("Bacillus globigii" Migula 1900)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, TOPSAN

Function

[THIG_BACSU] Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Park JH, Dorrestein PC, Zhai H, Kinsland C, McLafferty FW, Begley TP. Biosynthesis of the thiazole moiety of thiamin pyrophosphate (vitamin B1). Biochemistry. 2003 Oct 28;42(42):12430-8. PMID:14567704 doi:http://dx.doi.org/10.1021/bi034902z

1xm3, resolution 1.80Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1xm3&oldid=2441018"