A New Crystal Structure of the Drosophila melanogaster Angiotensin Converting Enzyme Homologue AnCE.A New Crystal Structure of the Drosophila melanogaster Angiotensin Converting Enzyme Homologue AnCE.

Structural highlights

5a2r is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Activity:Peptidyl-dipeptidase A, with EC number 3.4.15.1
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[ACE_DROME] May be involved in the specific maturation or degradation of a number of bioactive peptides. May play a role in the contractions of the heart, gut and testes, and in spermatid differentiation.[1]

References

  1. Hurst D, Rylett CM, Isaac RE, Shirras AD. The drosophila angiotensin-converting enzyme homologue Ance is required for spermiogenesis. Dev Biol. 2003 Feb 15;254(2):238-47. PMID:12591244

5a2r, resolution 1.85Å

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