Structural highlights
4zme is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , |
| NonStd Res: | |
| Related: | 3lla, 3lmh, 3lkm, 3lmi, 3pdt |
| Activity: | [Myosin_heavy-chain_kinase [Myosin heavy-chain] kinase], with EC number 2.7.11.7 |
| Resources: | FirstGlance, OCA, RCSB, PDBsum |
Function
[MHCKA_DICDI] Phosphorylates threonine in the C-terminal tail region of myosin II heavy chain. This phosphorylation is critical in regulating the assembly and disassembly of myosin II filament. Requires autophosphorylation for activity.