Receptor for activated protein kinase C 1

From Proteopedia
Revision as of 13:23, 23 July 2015 by Michal Harel (talk | contribs)
Jump to navigation Jump to search

Receptor for activated protein kinase C 1 (RACK1) is a scaffold protein which is able to interact simultaneously with several signaling molecules. It binds to protein kinases and to membrane-bound receptors. RACK1 is also part of the eukaryotic ribosome and it localizes to the small 40S subunit. RACK1 recruits activated protein kinase to the ribosome and allows translation to be linked to cellular stimuli.

Function

Disease

Relevance

Structural highlights

Human receptor for activated protein kinase C 1 complex with glycerol (PDB code 4aow)

Drag the structure with the mouse to rotate

3D Structures of receptor for activated protein kinase C 13D Structures of receptor for activated protein kinase C 1

Updated on 23-July-2015

3frx, 3rfg, 3rfh – yRACK1 – yeast
4aow – hRACK1 – human
1trj – yRACK1 + RNA – Cryo EM
3j6x, 3j6y, 4v6i, 4v7r, 3j77, 3j78, 4u3m, 4u3n, 4u3u, 4u4n, 4u4o, 4u4r, 4u4u, 4u4y, 4u4z, 4u50, 4u51, 4u52, 4u53, 4u55, 4u56, 4u6f – yRACK1 in y80S ribosome – Cryo EM
4v6x, 5aj0, 4ug0, 5a2q – hRACK1 in h80S ribosome – Cryo EM <br

ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel