5a2t

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The Molecular Basis for Flexibility in the Flexible Filamentous Plant VirusesThe Molecular Basis for Flexibility in the Flexible Filamentous Plant Viruses

Structural highlights

5a2t is a 26 chain structure with sequence from Bamboo mosaic virus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, RCSB, PDBsum

Publication Abstract from PubMed

Flexible filamentous plant viruses cause more than half the viral crop damage in the world but are also potentially useful for biotechnology. Structural studies began more than 75 years ago but have failed, owing to the virion's extreme flexibility. We have used cryo-EM to generate an atomic model for bamboo mosaic virus, which reveals flexible N- and C-terminal extensions that allow deformation while still maintaining structural integrity.

The molecular basis for flexibility in the flexible filamentous plant viruses.,DiMaio F, Chen CC, Yu X, Frenz B, Hsu YH, Lin NS, Egelman EH Nat Struct Mol Biol. 2015 Jul 13. doi: 10.1038/nsmb.3054. PMID:26167882[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

  1. DiMaio F, Chen CC, Yu X, Frenz B, Hsu YH, Lin NS, Egelman EH. The molecular basis for flexibility in the flexible filamentous plant viruses. Nat Struct Mol Biol. 2015 Jul 13. doi: 10.1038/nsmb.3054. PMID:26167882 doi:http://dx.doi.org/10.1038/nsmb.3054

5a2t, resolution 5.60Å

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