5ahn

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IMP-bound form of the D199N mutant of IMPDH from Pseudomonas aeruginosaIMP-bound form of the D199N mutant of IMPDH from Pseudomonas aeruginosa

Structural highlights

5ahn is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:IMP dehydrogenase, with EC number 1.1.1.205
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[Q9HXM5_PSEAE] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]

5ahn, resolution 1.65Å

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