Signalosome

COP9 (COnstitutive Photomorphogenesis 9) signalosome catalyzes the hydrolysis of NEDD8 protein from the cullin subunit of cullin-ring ubiquitin ligase. COP9 functions in the ubiquitin-proteasome pathway. COP9 contains 8 subunits and is homologous to the lid of the 26S proteasome.

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3D Structures of COP9 signalosome3D Structures of COP9 signalosome

Updated on 08-July-2015

4d0p – hCOP9 subunit 4 – human
1ufm – hCOP9 subunit 4 PCI domain - NMR
4f7o – hCOP9 subunit 5
4qft – hCOP9 subunit 6
4e0q, 4r14 – hCOP9 subunit 6 MPN domain
4d10, 4d18 – hCOP9 subunits 1,2,3,4,5,6,7A,8