Poly(A) RNA polymerase

Poly(A) RNA polymerase protein Cid1 (Caffeine-Induced Death protein 1) is involved in cell cycle arrest where it inhibits unscheduled mitosis. Cid1 is found in fission yeast. Cid1 exists in 3 forms: apo I consists of 4 subunits; apo II consists of 2 subunits; UTP-bound form consists of 4 subunits. The UTP-bound form has in its N-terminal domain a catalytic triad of Asp residues which binds the UTP.

spinqualitylabelsall models Cid1 complex with UTP (PDB code 4e80) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of poly(A) RNA polymerase protein Cid13D Structures of poly(A) RNA polymerase protein Cid1

Updated on 06-July-2015

4e7x, 4e8f – Cid1
4ud4, 4ud5 – Cid1 (mutant)
4e80 – Cid1 + UTP
4fh3 – Cid1 residues 33-377
4ep7, 4fh5, 4fhp – Cid1 residues 30-377 + UTP
4fhv – Cid1 residues 30-377 + CTP
4fhw – Cid1 residues 30-377 + GTP
4fhy – Cid1 residues 30-377 + ATP
4fhx – Cid1 residues 30-377 (mutant) + ATP
4nkt – Cid1 residues 30-377 + UMPNPP
4nku – Cid1 residues 40-377 (mutant) + dinucleotide