User:Gabriel Pons/Sandbox 3
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TGFβ signalling pathway
Ligands
TGFβ isoforms
TGFβ receptors
TGFβ receptor ectodomain
TGFβ receptor endodomain
TGFβ signalling
Latent TGFβ structure and activation
pro-TGFβ-1 processing
TGFβ-1:TβRII:TβRI ternary complex
TGFβ signalling pathwayTGFβ signalling pathway
load='2QCQ' size='400' side='right' TGFβ belongs to a group of extracellular signals involved in the regulation of several cellular processes as cell proliferation, differentiation, Apoptosis, development, cellular adhesion, immune surveillance and Tissue homeostasis. In addition they are involved in pathological conditions as autoimmune diseases, Inflammatory diseases, cancer and Cardiovascular diseases
LigandsLigands
TGFβ represents a paradigm of these group of ligands
TGFβ isoformsTGFβ isoforms
