3j9c

From Proteopedia
Revision as of 14:52, 11 March 2015 by OCA (talk | contribs)
Jump to navigation Jump to search

CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolutionCryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution

Structural highlights

3j9c is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.

3j9c, resolution 2.90Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA