4ds6

Crystal structure of a group II intron in the pre-catalytic stateCrystal structure of a group II intron in the pre-catalytic state

Structural highlights 4ds6 is a 1 chain structure with sequence from Oceanobacillus iheyensis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: Resources: FirstGlance, OCA, RCSB, PDBsum Publication Abstract from PubMed Group II introns are self-splicing catalytic RNAs that are thought to be ancestral to the spliceosome. Here we report the 3.65-A crystal structure of the group II intron from Oceanobacillus iheyensis in the pre-catalytic state. The structure reveals the conformation of the 5' splice site in the catalytic core and represents the first structure of an intron prior to the first step of splicing. Crystal structure of a group II intron in the pre-catalytic state.,Chan RT, Robart AR, Rajashankar KR, Pyle AM, Toor N Nat Struct Mol Biol. 2012 Apr 8. doi: 10.1038/nsmb.2270. PMID:22484319 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

spinqualitylabelsall models 4ds6, resolution 3.64Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image