2gzl
Structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with a CDP derived fluorescent inhibitor
| |||||||
| , resolution 2.50Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , and | ||||||
| Gene: | ispF, mecS (Escherichia coli) | ||||||
| Activity: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, with EC number 4.6.1.12 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
About this StructureAbout this Structure
2GZL is a Single protein structure of sequence from Escherichia coli. This structure supersedes the now removed PDB entry 2AO4. Full crystallographic information is available from OCA.
ReferenceReference
Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy., Crane CM, Kaiser J, Ramsden NL, Lauw S, Rohdich F, Eisenreich W, Hunter WN, Bacher A, Diederich F, Angew Chem Int Ed Engl. 2006 Feb 6;45(7):1069-74. PMID:16392111
Page seeded by OCA on Thu Mar 20 17:10:48 2008