1rcx

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Revision as of 17:53, 29 October 2007 by OCA (talk | contribs) (New page: left|200px<br /> <applet load="1rcx" size="450" color="white" frame="true" align="right" spinBox="true" caption="1rcx, resolution 2.4Å" /> '''NON-ACTIVATED SPINAC...)
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File:1rcx.gif


1rcx, resolution 2.4Å

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NON-ACTIVATED SPINACH RUBISCO IN COMPLEX WITH ITS SUBSTRATE RIBULOSE-1,5-BISPHOSPHATE

OverviewOverview

The three-dimensional structure of the complex of ribulose, 1,5-bisphosphate carboxylase/oxygenase (rubisco; EC 4.1.1.39) from spinach, with its natural substrate ribulose 1,5-bisphosphate (RuBP) has been, determined both under activating and non-activating conditions by X-ray, crystallography to a resolution of 2.1 A and 2.4 A, respectively. Under, activating conditions, the use of calcium instead of magnesium as the, activator metal ion enabled us to trap the substrate in a stable complex, for crystallographic analysis. Comparison of the structure of the, activated and the non-activated RuBP complexes shows a tighter binding for, the substrate in the non-activated form of the enzyme, in line with, previous solution studies. In the non-activated complex, the substrate, triggers isolation ... [(full description)]

About this StructureAbout this Structure

1RCX is a [Protein complex] structure of sequences from [Spinacia oleracea] with RUB as [ligand]. The following page contains interesting information on the relation of 1RCX with [Rubisco]. Active as [[1]], with EC number [4.1.1.39]. Full crystallographic information is available from [OCA].

ReferenceReference

The structure of the complex between rubisco and its natural substrate ribulose 1,5-bisphosphate., Taylor TC, Andersson I, J Mol Biol. 1997 Jan 31;265(4):432-44. PMID:9034362

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