1tgv

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Structure of E. coli Uridine Phosphorylase complexed with 5-Fluorouridine and sulfateStructure of E. coli Uridine Phosphorylase complexed with 5-Fluorouridine and sulfate

Structural highlights

1tgv is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:UDP, B3831 (Escherichia coli)
Activity:Uridine phosphorylase, with EC number 2.4.2.3
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[UDP_ECOLI] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1tgv, resolution 2.20Å

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