4hl1

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Crystal Structure of New Delhi Metallo-beta-Lactamase-1, Complexed with Cd and AmpicillinCrystal Structure of New Delhi Metallo-beta-Lactamase-1, Complexed with Cd and Ampicillin

Structural highlights

4hl1 is a 2 chain structure with sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:blaNDM-1 (Klebsiella pneumoniae)
Activity:Beta-lactamase, with EC number 3.5.2.6
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.

See Also

4hl1, resolution 1.50Å

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