2m5e

Structure of the C-domain of Calcium-saturated Calmodulin bound to the IQ motif of NaV1.2Structure of the C-domain of Calcium-saturated Calmodulin bound to the IQ motif of NaV1.2

Structural highlights 2m5e is a 2 chain structure. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: Related: 2kxw, 1exr Resources: FirstGlance, OCA, RCSB, PDBsum Function [CALM_PARTE] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. [SCN2A_RAT] Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.

spinqualitylabelsall models 2m5e, 21 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image