2xdr

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CRYSTALLOGRAPHIC STRUCTURE OF BETAINE ALDEHYDE DEHYDROGENASE MUTANT E252A FROM PSEUDOMONAS AERUGINOSACRYSTALLOGRAPHIC STRUCTURE OF BETAINE ALDEHYDE DEHYDROGENASE MUTANT E252A FROM PSEUDOMONAS AERUGINOSA

Structural highlights

2xdr is a 4 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Activity:Betaine-aldehyde dehydrogenase, with EC number 1.2.1.8
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[BETB_PSEAE] Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.[1]

See Also

References

  1. ↑ Diaz-Sanchez AG, Gonzalez-Segura L, Rudino-Pinera E, Lira-Rocha A, Torres-Larios A, Munoz-Clares RA. Novel NADPH-cysteine covalent adduct found in the active site of an aldehyde dehydrogenase. Biochem J. 2011 Nov 1;439(3):443-52. PMID:21732915 doi:10.1042/BJ20110376

2xdr, resolution 2.30Å

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OCA
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