4a1n

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Human Mitochondrial endo-exonucleaseHuman Mitochondrial endo-exonuclease

Structural highlights

4a1n is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[EXOG_HUMAN] Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.[1]

References

  1. ↑ Cymerman IA, Chung I, Beckmann BM, Bujnicki JM, Meiss G. EXOG, a novel paralog of Endonuclease G in higher eukaryotes. Nucleic Acids Res. 2008 Mar;36(4):1369-79. doi: 10.1093/nar/gkm1169. Epub 2008, Jan 10. PMID:18187503 doi:http://dx.doi.org/10.1093/nar/gkm1169

4a1n, resolution 2.80Å

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OCA
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