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4a35

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CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 (ENOSF1)CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 (ENOSF1)

Structural highlights

4a35 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[ENOF1_HUMAN] May regulate thymidylate synthase activity.[1] [2]

References

  1. ↑ Dolnick BJ, Black AR, Winkler PM, Schindler K, Hsueh CT. rTS gene expression is associated with altered cell sensitivity to thymidylate synthase inhibitors. Adv Enzyme Regul. 1996;36:165-80. PMID:8869746
  2. ↑ Dolnick BJ, Angelino NJ, Dolnick R, Sufrin JR. A novel function for the rTS gene. Cancer Biol Ther. 2003 Jul-Aug;2(4):364-9. PMID:14508106

4a35, resolution 1.74Å

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