4g4z

Crystal structure of OmpA peptidoglycan-binding domain from Acinetobacter baumanniiCrystal structure of OmpA peptidoglycan-binding domain from Acinetobacter baumannii

Structural highlights

4g4z is a 8 chain structure with sequence from Acinetobacter baumannii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	,
Related:	4g4v, 4g4w, 4g4x, 4g4y, 4g88
Gene:	omp38, ompA (Acinetobacter baumannii)
Resources:	FirstGlance, OCA, RCSB, PDBsum

Function

[OMP38_ACIBA] Porin. Induces apoptosis in human laryngeal epithelial HEp-2 cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor).^[1] ^[2]

References

↑ Choi CH, Lee EY, Lee YC, Park TI, Kim HJ, Hyun SH, Kim SA, Lee SK, Lee JC. Outer membrane protein 38 of Acinetobacter baumannii localizes to the mitochondria and induces apoptosis of epithelial cells. Cell Microbiol. 2005 Aug;7(8):1127-38. PMID:16008580 doi:CMI538
↑ Jyothisri K, Deepak V, Rajeswari MR. Purification and characterization of a major 40 kDa outer membrane protein of Acinetobacter baumannii. FEBS Lett. 1999 Jan 22;443(1):57-60. PMID:9928952

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Choi CH, Lee EY, Lee YC, Park TI, Kim HJ, Hyun SH, Kim SA, Lee SK, Lee JC. Outer membrane protein 38 of Acinetobacter baumannii localizes to the mitochondria and induces apoptosis of epithelial cells. Cell Microbiol. 2005 Aug;7(8):1127-38. PMID:16008580 doi:CMI538

[2] Jyothisri K, Deepak V, Rajeswari MR. Purification and characterization of a major 40 kDa outer membrane protein of Acinetobacter baumannii. FEBS Lett. 1999 Jan 22;443(1):57-60. PMID:9928952

[1]

[2]

4g4z

Crystal structure of OmpA peptidoglycan-binding domain from Acinetobacter baumanniiCrystal structure of OmpA peptidoglycan-binding domain from Acinetobacter baumannii

Structural highlights

Function

References

Contents

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

4g4z

Crystal structure of OmpA peptidoglycan-binding domain from Acinetobacter baumanniiCrystal structure of OmpA peptidoglycan-binding domain from Acinetobacter baumannii

Structural highlights

Function

References

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

Search