2rf0

Crystal structure of human mixed lineage kinase MAP3K10 SH3 domainCrystal structure of human mixed lineage kinase MAP3K10 SH3 domain

Structural highlights 2rf0 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: Related: 1oeb, 1fmk Gene: MAP3K10, MLK2, MST (Homo sapiens) Activity: Mitogen-activated protein kinase kinase kinase, with EC number 2.7.11.25 Resources: FirstGlance, OCA, RCSB, PDBsum Function [M3K10_HUMAN] Activates the JUN N-terminal pathway (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Mitogen-activated protein kinase kinase kinase

spinqualitylabelsall models 2rf0, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image