Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamideStructural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide

Structural highlights

4nnk is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[RS1_MYCTU] Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).

4nnk, resolution 2.31Å

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OCA