Tryptophan RNA-binding attenuation protein

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Function

Tryptophan RNA-binding attenuation protein (TRAP) is a tryptophan-activated RNA-binding protein which regulates the expression of the tryptophan biosynthesis genes. TRAP is composed of 11 identical subunits arranged in a symmetrical ring. Down regulation of Trp biosynthesis is observed upon binding of 11 Trp to TRAP.

Disease

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Structural highlights

Structure of tryptophan RNA-binding attenuation protein complex with RNA and Trp (PDB code 1utf).

Drag the structure with the mouse to rotate

3D Structures of tryptophan RNA-binding attenuation protein3D Structures of tryptophan RNA-binding attenuation protein

Updated on 15-December-2014 {{#tree:id=OrganizedByTopic|openlevels=0|

  • Tryptophan RNA-binding attenuation protein
    • 3aqd – GsTRAP – Geobacillus stearothermophilus
  • Tryptophan RNA-binding attenuation protein binary complex with Trp
    • 2zdo, 2exs, 2ext, 2zcz, 2zd0 – GsTRAP + Trp
    • 1wap, 3zzq – BsTRAP + Trp – Bacillus subtilis
    • 4b27 – BsTRAP (mutant) + Trp
    • 3zte – TRAP + Trp – Bacillus licheniformis
    • 3zzl – TRAP + Trp – Bacillus halodurans
  • Tryptophan RNA-binding attenuation protein ternary complex with Trp


ReferencesReferences

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky