Signal recognition particle receptor

spinqualitylabelsall models Human SRPR α (grey) and β subunit (green) complex with GTP (stick model) and Mg+2 (green) ion 2fh5 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Signal recognition particle receptor (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the signal recognition particle (SRP). SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called FtsY.

3D structures of signal recognition particle receptor3D structures of signal recognition particle receptor

Updated on 10-December-2014

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• Signal recognition particle receptor
  • 1nrj – ySRPR α+β subunits + GTP – yeast
    
  • 2fh5 - hSRPR α+β subunits + GTP – human
    
  • 2ged - ySRPR β subunit (mutant)
    
  • 2go5 - hSRPR α subunit + mSRPR β subunit + ribosomal proteins L23, L31, L35 + dSRP19 + dSRP54 + RNA - EM
    
  • 3dm9, 3dmd, 3e70 – SRPR + GDP – Pyrococcus furiosus
• Signal recognition particle receptor FtsY
  • 1zu5, 1zu4 – SRPR FtsY NG domain – Mycoplasma mycoides
    
  • 1vma – SRPR FtsY – Thermotoga maritima
    
  • 2yhs, 2qy9, 1fts – EcSRPR FtsY NG domain – Escherichia coli
    
  • 2q9a – EcSRPR FtsY
    
  • 2q9c, 2q9b – EcSRPR FtsY NG domain + GMPPNP
    
  • 2iyl – EcSRPR FtsY residues 20-303 + GDP
    
  • 2xxa - EcSRPR FtsY NG domain + signal recognition particle protein residues 1-433 (mutant) + 4.5SRNA
    
  • 3zn8 - EcSRPR FtsY NG domain + signal recognition particle protein 54 NG domain + 4.5SRNA + dipeptidyl aminopeptidase B
    
  • 2j7p, 1rj9, 1okk – TaSRPR FtsY NG domain + signal recognition particle protein – Thermus aquaticus
    
  • 2cnw – TaSRPR FtsY NG domain + signal recognition particle protein + GDP
    
  • 4c7o – EcFtsY + EcSRP + SRP RNA
    
  • 2xkv – EcFtsY + EcSRP NG+M domains + 4.5S RNA