Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor bindingConformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding

Structural highlights

3mpa is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2 (Homo sapiens)
Activity:Mitogen-activated protein kinase, with EC number 2.7.11.24
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3mpa, resolution 2.10Å

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OCA