Metabotropic glutamate receptor

Metabotropic glutamate receptors are glutamate receptors that activate ion channels indirectly through a signalling cascade involving G proteins. They are members of the large class of seven-transmembrane domain receptors, the G protein-coupled receptors.

spinqualitylabelsall models Structure of the binding domain of the Metabotropic Glutamate Receptor, GluR1, bound to glutamateand gadolinium ions (1isr) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Articles in Proteopedia concerning Toll-like Receptors include:

• Leucine-rich repeat
• Membrane proteins

3D structures of metabotropic glutamate receptor3D structures of metabotropic glutamate receptor

Updated on 01-December-2014

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• Metabotropic glutamate receptor 1
  • 1ewt, 1ewv - rMGluR1 ligand-binding domain
    
  • 3ks9 – hMGluR1 (mutant) + antagonist
    
  • 4or2 - hMGluR1/cytochrome b526
    
  • 1isr, 1ewk – rMGluR1 ligand-binding domain + Glu
    
  • 1iss - rMGluR1 ligand-binding domain + antagonist
    
• Metabotropic glutamate receptor 3
  • 2e4u – hMGluR3 ligand-binding domain (mutant) + Glu
    
  • 2e4v, 2e4w, 2e4x, 2e4y, 2e4z - hMGluR3 ligand-binding domain (mutant) + agonist
    
  • 3sm9 - hMGluR3 + antagonist
    
• Metabotropic glutamate receptor 5
  • 3lmk – hMGluR5 ligand-binding domain (mutant) + positive allosteric modulator + Glu
    
• Metabotropic glutamate receptor 7
  • 3mq4 – hMGluR7 ligand-binding domain + antagonist
    

See AlsoSee Also

Membrane Channels & Pumps
Ionotropic_Glutamate_Receptors
Alzheimer's Disease

• Ligand Binding N-Terminal of Metabotropic Glutamate Receptors