Telomerase 3D structures

Updated on 06-November-2014 - For a general description of the protein see Telomerase

3kyl, 3du5, 3du6 – TERT+DNA – Tribolium castaneum
2r4g – TtTERT RNA binding domain – Tetrahymena thermophila
2b2a – TtTERT (mutant)
2fey - TtTERC RNA P2b hairpin – NMR
1q75, 2k96 – hTERC RNA P2b hairpin (mutant) – human – NMR
2k95 - hTERC RNA P2b hairpin – NMR
2qh2 - hTERC RNA CR7– NMR
1na2, 1ymo - hTERC RNAstem loop IV– NMR
1z31 - hTERC RNA Pj6 hairpin – NMR

Telomerase (TEL) adds DNA repeats to the tail end of telomeres. It carries its own RNA. The human TEL is composed of 2 Telomerase Reverse Transcriptase (TERT), 2 Telomerase RNA (TERC) and 2 dyskerin (DKC1) molecules. For additional details see Catalytic Subunit of T. Castaneum TERT Polymerase.