Gramicidin Channel in Lipid Bilayer

Theoretical Model: The structure described on this page was determined theoretically, and hence should be interpreted with caution.

spinqualitylabelsall models Theoretical model of gramicidin in a lipid bilayer (phosphatidyl ethanolamine). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

We apologize, but most of the scenes (green links) on this page are broken. We are working to repair this page. Eric Martz 03:07, 16 August 2014 (IDT)

TEST FOR DEVELOPMENT:

Two copies of the 15-amino-acid gramicidin protein are shown here () arranged as they are believed to be when they form a channel through a lipid bilayer membrane. The shape of the protein is shown transparent (ghostly), and a backbone trace connecting the alpha carbon atoms of each amino acid chain is opaque (solid). Toggle spin off to see transparency.

• Show of the gramicidin protein chains.
• (Most hydrogen atoms are omitted.)
• Show . Notice how the hydrophobic lipid "tails" exclude water.
• Water passes . Toggle spin off to see transparency.
• Show .
• Show only . For an explanation of their structure, see the detailed tutorial, also disponible en español.

Remember to use the popup button and then resize the popup window to enlarge the molecular scenes.

See AlsoSee Also

• A detailed explanation and tutorial about Lipid Bilayers and the Gramicidin Channel.
• This model in FirstGlance in Jmol. Be sure to click the Ligands+ and Water buttons!
• BioMolecular Explorer 3D, a resource for high school teachers that includes a section on gramicidin in a lipid bilayer.
• High school teachers' resources
• The Spanish version of this page: Canal de gramicidina en bicapa lipídica (Spanish)
• For additional information, see: Membrane Channels & Pumps

NotesNotes

• The PDB file shown here, File:Gramicidin in bilayer.pdb.gz, was kindly provided by Serge Crouzy.
• To load the scenes on this page into the SAT, change the page name to User:Eric_Martz/Sandbox_10, where these scenes were developed.