1qpv

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YEAST COFILINYEAST COFILIN

Structural highlights

1qpv is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Related:1cfy, 1cof
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Cofilin, a ubiquitous 15,000 M(r) protein, plays a central role in regulating cytoskeletal dynamics. Cofilin binds to actin monomers and filaments, and has a pH-dependent actin severing activity. The structure will allow for a detailed analysis of cofilin function.

Structure determination of yeast cofilin.,Fedorov AA, Lappalainen P, Fedorov EV, Drubin DG, Almo SC Nat Struct Biol. 1997 May;4(5):366-9. PMID:9145106[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

  1. Fedorov AA, Lappalainen P, Fedorov EV, Drubin DG, Almo SC. Structure determination of yeast cofilin. Nat Struct Biol. 1997 May;4(5):366-9. PMID:9145106

1qpv, resolution 3.00Å

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