2kys

NMR Structure of the SARS Coronavirus Nonstructural Protein Nsp7 in Solution at pH 6.5NMR Structure of the SARS Coronavirus Nonstructural Protein Nsp7 in Solution at pH 6.5

Structural highlights 2kys is a 1 chain structure with sequence from Sars coronavirus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: 1a (SARS coronavirus) Resources: FirstGlance, OCA, RCSB, PDBsum Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed The NMR structure of the severe acute respiratory syndrome coronavirus nonstructural protein (nsp) 7 in aqueous solution at pH 6.5 was determined and compared with the results of previous structure determinations of nsp7 in solution at pH 7.5 and in the crystals of a hexadecameric nsp7/nsp8 complex obtained from a solution at pH 7.5. All three structures contain four helices as the only regular secondary structures, but there are differences in the lengths and sequence locations of the four helices, as well as between the tertiary folds. The present study includes data on conformational equilibria and intramolecular rate processes in nsp7 in solution at pH 6.5, which provide further insights into the polymorphisms implicated by a comparison of the three presently available nsp7 structures. NMR Structure of the SARS-CoV Nonstructural Protein 7 in Solution at pH 6.5.,Johnson MA, Jaudzems K, Wuthrich K J Mol Biol. 2010 Oct 1;402(4):619-28. Epub 2010 Aug 13. PMID:20709084 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Nonstructural protein

spinqualitylabelsall models 2kys, 20 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image