1n7a

RIP-Radiation-damage Induced PhasingRIP-Radiation-damage Induced Phasing

Structural highlights 1n7a is a 8 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , NonStd Res: Related: 1n7b, 1n6x, 1n6y Resources: FirstGlance, OCA, RCSB, PDBsum Publication Abstract from PubMed The use of third generation synchrotron sources has led to renewed concern about the effect of ionizing radiation on crystalline biological samples. In general, the problem is seen as one to be avoided. However, in this paper, it is shown that, far from being a hindrance to successful structure determination, radiation damage provides an opportunity for phasing macromolecular structures. This is successfully demonstrated for both a protein and an oligonucleotide, by way of which complete models were built automatically. The possibility that, through the exploitation of radiation damage, the phase problem could become less of a barrier to macromolecular crystal structure determination is discussed. Specific radiation damage can be used to solve macromolecular crystal structures.,Ravelli RB, Leiros HK, Pan B, Caffrey M, McSweeney S Structure. 2003 Feb;11(2):217-24. PMID:12575941 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

spinqualitylabelsall models 1n7a, resolution 1.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image