1na7

Crystal structure of the catalytic subunit of human protein kinase CK2Crystal structure of the catalytic subunit of human protein kinase CK2

Structural highlights 1na7 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 1a6o, 1f0q, 1m2q, 1m2r Activity: Non-specific serine/threonine protein kinase, with EC number 2.7.11.1 Resources: FirstGlance, OCA, RCSB, PDBsum Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed The three-dimensional crystal structure of the triple-point mutant of the catalytic subunit of human protein kinase CK2alpha has been determined at 2.4 A resolution. Microcrystals of mutant CK2 catalytic subunit were obtained by a protein-crystallization method based on thin-film nanotechnology. These microcrystals (of about 20 micro m in diameter) were used for diffraction data collection by means of the microfocus beamline at the ESRF synchrotron. A comparison between the human protein kinase CK2alpha and the corresponding enzyme from a lower organism (Zea mays) is made. Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.,Pechkova E, Zanotti G, Nicolini C Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2133-9. Epub 2003, Nov 27. PMID:14646071 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Casein kinase

spinqualitylabelsall models 1na7, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image