1mp6

Structure of the transmembrane region of the M2 protein H+ channel by solid state NMR spectroscopyStructure of the transmembrane region of the M2 protein H+ channel by solid state NMR spectroscopy

Structural highlights 1mp6 is a 1 chain structure. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, RCSB, PDBsum Publication Abstract from PubMed The transmembrane domain of the M2 protein from influenza A virus forms a nearly uniform and ideal helix in a liquid crystalline bilayer environment. The exposure of the hydrophilic backbone structure is minimized through uniform hydrogen bond geometry imposed by the low dielectric lipid environment. A high-resolution structure of the monomer backbone and a detailed description of its orientation with respect to the bilayer were achieved using orientational restraints from solid-state NMR. With this unique information, the tetrameric structure of this H(+) channel is constrained substantially. Features of numerous published models are discussed in light of the experimental structure of the monomer and derived features of the tetrameric bundle. Structure of the transmembrane region of the M2 protein H(+) channel.,Wang J, Kim S, Kovacs F, Cross TA Protein Sci. 2001 Nov;10(11):2241-50. PMID:11604531 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Ion channels M2 protein

spinqualitylabelsall models 1mp6, 1 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image