Estrogen-related receptor

Template:STRUCTURE 2gpv

Estrogen-related receptor (ERR) binds to estrogen response elements on DNA and modulates transcription in response to hormone. ERR plays a role in energy homeostasis and cancer. There are 3 classes of ERR : ERRα, ERRβ and ERRγ.

3D structures of estrogen-related receptor3D structures of estrogen-related receptor

Updated on 18-August-2014

ERRERR

1xb7, 3d24 – hERR ligand-binding domain + peroxisome proliferator activated receptor coactivator 1 peptide – human
2pjl - hERR ligand-binding domain (mutant) + inverse agonist
3k6p - hERR ligand-binding domain + ligand

ERRβERRβ

1lo1 – hERR DNA-binding domain + DNA - NMR

ERRγERRγ

2gp7, 2zbs - hERR ligand-binding domain
1kv6, 1tfc – hERR ligand-binding domain + steroid receptor coactivator 1 2nd NR-Box
2gpo, 2gpp - hERR ligand-binding domain + nuclear receptor-interacting protein 1 peptide
2ewp - hERR ligand-binding domain + tamoxifen analog
2gpu, 2p7z - hERR ligand-binding domain + 4-hydroxytamoxifen
2e2r, 2p7g - hERR ligand-binding domain + bisphenol A
2zkc - hERR ligand-binding domain + bisphenol Z
2zas - hERR ligand-binding domain + bisphenol A derivative
2p7a - hERR ligand-binding domain + methyl phenol
2gpv - hERR ligand-binding domain + nuclear receptor corepressor 2 peptide + 4-hydroxytamoxifen
1s9p, 1s9q - mERR ligand-binding domain + diethylstilbesterol – mouse
1vjb - mERR ligand-binding domain + 4-hydroxytamoxifen

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Wayne Decatur, Alexander Berchansky