1hqz
Cofilin homology domain of a yeast actin-binding protein ABP1PCofilin homology domain of a yeast actin-binding protein ABP1P
Template:ABSTRACT PUBMED 15735338
FunctionFunction
[ABP1_YEAST] Regulates ARP2/3 complex-mediated actin assembly. Recruits ARP2/3 complex to sides of preexisting actin filaments, which may promote nucleation or stabilization of filament branches. Binds to actin filaments, but not actin monomers. Actin binding is required for ARP2/3 complex activation. May also have a role in linking the actin cytoskeleton to endocytosis. recruits components of the endocytotic machinery to cortical actin patches, known sites of endocytosis.[1]
About this StructureAbout this Structure
1hqz is a 9 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Strokopytov BV, Fedorov A, Mahoney NM, Kessels M, Drubin DG, Almo SC. Phased translation function revisited: structure solution of the cofilin-homology domain from yeast actin-binding protein 1 using six-dimensional searches. Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):285-93. Epub 2005, Feb 24. PMID:15735338 doi:10.1107/S0907444904033037
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OCACategories:
- Saccharomyces cerevisiae
- Almo, S C.
- Burley, S K.
- Drubin, D G.
- Fedorov, A A.
- Mahoney, N.
- NYSGXRC, New York SGX Research Center for Structural Genomics.
- Strokopytov, B V.
- Actin binding
- Cofilin homology domain
- New york sgx research center for structural genomic
- Nysgxrc
- Protein structure initiative
- Psi
- Structural genomic
- Structural protein