4naz

Crystal Structure of FosB from Staphylococcus aureus with Zn and Sulfate at 1.15 Angstrom ResolutionCrystal Structure of FosB from Staphylococcus aureus with Zn and Sulfate at 1.15 Angstrom Resolution

FunctionFunction

[FOSB_STAAN] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity).

About this StructureAbout this Structure

4naz is a 1 chain structure with sequence from Staan. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Thompson MK, Keithly ME, Goodman MC, Hammer ND, Cook PD, Jagessar KL, Harp J, Skaar EP, Armstrong RN. Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry. 2014 Feb 4;53(4):755-65. doi: 10.1021/bi4015852. Epub 2014 Jan 21. PMID:24447055 doi:http://dx.doi.org/10.1021/bi4015852

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Thompson MK, Keithly ME, Goodman MC, Hammer ND, Cook PD, Jagessar KL, Harp J, Skaar EP, Armstrong RN. Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry. 2014 Feb 4;53(4):755-65. doi: 10.1021/bi4015852. Epub 2014 Jan 21. PMID:24447055 doi:http://dx.doi.org/10.1021/bi4015852

[xtra 1]