3fpb

Ligands:

, , , ,

Activity:

Calcium-transporting ATPase, with EC number 3.6.3.8

Related:

Structural annotation:
Resources:	CATH : 3Fpba02, 3Fpba03, 3Fpba04, 3Fpba01 InterPro : Ipr000695, Ipr001757, Ipr004014, Ipr005782, Ipr005834, Ipr006068, Ipr023306, Ipr018303, Ipr023214, Ipr023298, Ipr023299, Ipr023300, Ipr008250 Pfam : PF00122, PF00702, PF00690, PF00689

Evolutionary conservation:

Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

The Structure of Sarcoplasmic Reticulum Ca2+-ATPase Bound To Cyclopiazonic acid with ATPThe Structure of Sarcoplasmic Reticulum Ca2+-ATPase Bound To Cyclopiazonic acid with ATP

Template:ABSTRACT PUBMED 19289472

FunctionFunction

[AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).

About this StructureAbout this Structure

3fpb is a 1 chain structure with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Laursen M, Bublitz M, Moncoq K, Olesen C, Moller JV, Young HS, Nissen P, Morth JP. Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase. J Biol Chem. 2009 May 15;284(20):13513-8. Epub 2009 Mar 16. PMID:19289472 doi:10.1074/jbc.C900031200

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OCA

[1] Laursen M, Bublitz M, Moncoq K, Olesen C, Moller JV, Young HS, Nissen P, Morth JP. Cyclopiazonic acid is complexed to a divalent metal ion when bound to the sarcoplasmic reticulum Ca2+-ATPase. J Biol Chem. 2009 May 15;284(20):13513-8. Epub 2009 Mar 16. PMID:19289472 doi:10.1074/jbc.C900031200

[xtra 1]