Molecular Playground/ClyA
<Structure load='1qoy' size='350' frame='true' align='left' caption='ClyA monomer in its inactive form' scene='<scene name='57/571278/Clya_monomer/1'>
About this StructureAbout this Structure
1QOY is a monomer from the dodecameric pore-forming toxin from Escherichia coli. It is comprised of four alpha helicies and a smaller fifth alpha helix. Though its crystal structure,2WCD revealed a dodecamer, larger pores have been isolated, as well.
File:ClyA.png File:ClyA-protomer.png
Research on ClyA at UMass AmherstResearch on ClyA at UMass Amherst
The Chen Lab, in collaboration with the Heuck lab, recently published a paper on ClyA assembly.