Template:STRUCTURE 4kas

Crystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMPCrystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMP

Template:ABSTRACT PUBMED 24563811

FunctionFunction

[THYX_THEMA] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate.

About this StructureAbout this Structure

4kas is a 4 chain structure. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Mathews II. Flavin-Dependent Thymidylate Synthase as a Drug Target for Deadly Microbes: Mutational Study and a Strategy for Inhibitor Design. J Bioterror Biodef. 2013 Apr 20;Suppl 12:004. PMID:24563811 doi:http://dx.doi.org/10.4172/2157-2526.S12-004

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OCA