3cbk
chagasin-cathepsin Bchagasin-cathepsin B
Template:ABSTRACT PUBMED 18515357
FunctionFunction
[CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
About this StructureAbout this Structure
3cbk is a 2 chain structure. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Redzynia I, Ljunggren A, Abrahamson M, Mort JS, Krupa JC, Jaskolski M, Bujacz G. Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B. J Biol Chem. 2008 Aug 15;283(33):22815-25. Epub 2008 May 30. PMID:18515357 doi:10.1074/jbc.M802064200