Factor XIII

Crystal Structure of human Factor XIII, 1ggt

Factor XIII (FXIII) belongs to the blood coagulation system and crosslinks fibrin resulting in an insoluble clot. FXIII is activated by thrombin which cleaves it and releases an activation peptide. The images at the left and at the right correspond to one representative FXIII, i.e. the crystal structure of human Factor XIII (1ggt).

3D Structures of Factor XIII3D Structures of Factor XIII

Updated on 05-March-2014

1ggt – hFXIII - human
1ex0 – hFXIII zymogen (mutant)
1fie – hFXIII subunit A
1f13 - hFXIII zymogen subunit A dimer
4kty - hFXIII subunit A + peptide-like ligand
1ggy, 1qrk, 1ggu, 1evu – hFXIII + ion
1de7 – fFXIII activation peptide + α-thrombin

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel