4lj6
ClpB NBD2 from T. thermophilus in complex with AMPPCPClpB NBD2 from T. thermophilus in complex with AMPPCP
FunctionFunction
[CLPB_THET8] Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.[1]
About this StructureAbout this Structure
4lj6 is a 1 chain structure. Full crystallographic information is available from OCA.