4j2r
Middle domain of influenza A virus RNA-dependent polymerase PB2Middle domain of influenza A virus RNA-dependent polymerase PB2
Template:ABSTRACT PUBMED 24419622
FunctionFunction
[PB2_I34A1] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity).
About this StructureAbout this Structure
4j2r is a 2 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Tsurumura T, Qiu H, Yoshida T, Tsumori Y, Tsuge H. Crystallization and preliminary X-ray diffraction studies of a surface mutant of the middle domain of PB2 from human influenza A (H1N1) virus. Acta Crystallogr F Struct Biol Commun. 2014 Jan;70(Pt 1):72-5. doi:, 10.1107/S2053230X13032603. Epub 2013 Dec 24. PMID:24419622 doi:http://dx.doi.org/10.1107/S2053230X13032603