3b7o
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Crystal structure of the human tyrosine phosphatase SHP2 (PTPN11) with an accessible active site
DiseaseDisease
Known diseases associated with this structure: Leopard syndrome OMIM:[176876], Leukemia, juvenile myelomonocytic OMIM:[176876], Noonan syndrome 1 OMIM:[176876]
About this StructureAbout this Structure
3B7O is a Single protein structure of sequence from Homo sapiens with as ligand. Active as Protein-tyrosine-phosphatase, with EC number 3.1.3.48 Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 19:03:55 2008
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Protein-tyrosine-phosphatase
- Single protein
- Arrowsmith, C H.
- Barr, A.
- Delft, F von.
- Edwards, A M.
- Elkins, J.
- King, O.
- Knapp, S.
- Niesen, F.
- Patel, A.
- Pilka, E S.
- SGC, Structural Genomics Consortium.
- Salah, E.
- Savitsky, P.
- Ugochukwu, E.
- Weigelt, J.
- MLT
- Alternative splicing
- Cytoplasm
- Deafness
- Disease mutation
- Hydrolase
- Phosphorylation
- Protein phosphatase
- Ptpn11
- Sgc
- Sh2 domain
- Shp2
- Structural genomics
- Structural genomics consortium
- Tyrosine phosphatase