Template:STRUCTURE 4npk

Extended-Synaptotagmin 2, C2A- and C2B-domains, calcium boundExtended-Synaptotagmin 2, C2A- and C2B-domains, calcium bound

Template:ABSTRACT PUBMED 24373768

FunctionFunction

[ESYT2_HUMAN] May play a role as calcium-regulated intrinsic membrane protein.[1]

About this StructureAbout this Structure

4npk is a 1 chain structure. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Xu J, Bacaj T, Zhou A, Tomchick DR, Sudhof TC, Rizo J. Structure and Ca-Binding Properties of the Tandem C Domains of E-Syt2. Structure. 2013 Dec 24. pii: S0969-2126(13)00461-9. doi:, 10.1016/j.str.2013.11.011. PMID:24373768 doi:http://dx.doi.org/10.1016/j.str.2013.11.011
  1. Min SW, Chang WP, Sudhof TC. E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3823-8. Epub 2007 Feb 28. PMID:17360437 doi:http://dx.doi.org/0611725104

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OCA