3agc

F218V mutant of the substrate-bound red chlorophyll catabolite reductase from Arabidopsis thalianaF218V mutant of the substrate-bound red chlorophyll catabolite reductase from Arabidopsis thaliana

Template:ABSTRACT PUBMED 20727901

FunctionFunction

[RCCR_ARATH] Catalyzes the key reaction of chlorophyll catabolism, porphyrin macrocycle cleavage of pheophorbide a (pheide a) to a primary fluorescent catabolite (pFCC). Works in a two-step reaction with pheophorbide a oxygenase (PaO) by reducing the C20/C1 double bond of the intermediate, RCC.^[1]

About this StructureAbout this Structure

3agc is a 2 chain structure with sequence from Arath. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Sugishima M, Okamoto Y, Noguchi M, Kohchi T, Tamiaki H, Fukuyama K. Crystal Structures of the Substrate-Bound Forms of Red Chlorophyll Catabolite Reductase: Implications for Site-Specific and Stereospecific Reaction. J Mol Biol. 2010 Aug 19. PMID:20727901 doi:10.1016/j.jmb.2010.08.021

↑ Wuthrich KL, Bovet L, Hunziker PE, Donnison IS, Hortensteiner S. Molecular cloning, functional expression and characterisation of RCC reductase involved in chlorophyll catabolism. Plant J. 2000 Jan;21(2):189-98. PMID:10743659

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OCA

[2] Sugishima M, Okamoto Y, Noguchi M, Kohchi T, Tamiaki H, Fukuyama K. Crystal Structures of the Substrate-Bound Forms of Red Chlorophyll Catabolite Reductase: Implications for Site-Specific and Stereospecific Reaction. J Mol Biol. 2010 Aug 19. PMID:20727901 doi:10.1016/j.jmb.2010.08.021

[1] Wuthrich KL, Bovet L, Hunziker PE, Donnison IS, Hortensteiner S. Molecular cloning, functional expression and characterisation of RCC reductase involved in chlorophyll catabolism. Plant J. 2000 Jan;21(2):189-98. PMID:10743659

[1]

[xtra 1]