4mz1
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12
FunctionFunction
[Q0P9J4_CAMJE] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
About this StructureAbout this Structure
4mz1 is a 3 chain structure. Full crystallographic information is available from OCA.
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- IMP dehydrogenase
- Anderson, W F.
- CSGID, Center for Structural Genomics of Infectious Diseases.
- Csgid
- Gu, M.
- Joachimiak, A.
- Kim, Y.
- Makowska-Grzyska, M.
- Alpha-beta structure
- Center for structural genomics of infectious disease
- National institute of allergy and infectious disease
- Niaid
- Oxidoreductase-oxidoreductase inhibitor complex
- Structural genomic
- Tim barrel